El presente trabajo investigativo hace referencia al papel central que ejercen las mujeres en la sociedad; y en particular, se abordará a la mujer candidata. En este contexto, hay que señalar que el Ecuador como cualquier otro país tiene su propia forma de gobernar, derivada de su historia política, económica y cultural. Este trabajo principalmente hace una prospección bibliográfica que da cuenta de las tendencias, fortalezas y desafíos que enfrentan las mujeres candidatas; y, el papel del dinero como elemento clave (...) de la política y las elecciones. La lectura de este trabajo se vuelve enriquecedora para quien quiera acercarse al estudio de la cultura política y participativa de las mujeres, lo cual permitirá a su vez, que este artículo esté mucho más cercano a la realidad ecuatoriana. (shrink)

El presente artículo hace referencia al papel central que ejercen los medios de comunicación en la sociedad. En este contexto, es preciso que aquellos ofrezcan una percepción adecuada y apegada a la realidad, lo cual involucra el abordaje de la discapacidad y los derechos de las personas que se encuentran en esa condición. Este trabajo principalmente hace una prospección bibliográfica que da cuenta de las tendencias, fortalezas y desafíos de los contenidos de los medios de comunicación. La lectura de este (...) trabajo se vuelve enriquecedora para quien quiera acercarse al estudio de la discapacidad y de los medios de comunicación como cuestión de derechos humanos, lo cual permitirá a su vez, que este artículo esté mucho más cercano a la realidad ecuatoriana. (shrink)

Background: Serious games have shown positive results in increasing motivation, adherence to treatment and strengthening the therapeutic alliance in multiple psychiatric disorders. In particular, patients with impulse control disorders and other disorders in which the patient suffers from inhibitory control deficits have been shown to benefit from serious games.Aim: The aim of this study was to describe the characteristics and to evaluate the usability of a new serious videogame, e-Estesia. This serious videogame was designed to improve emotion regulation in patients (...) with gambling disorder. Preliminary results from a pilot sample are also reported.Method: A pilot sample of 26 patients undergoing treatment for GD was recruited. Participants used e-Estesia on a tablet, which was connected to a thoracic band that sent heart rate and heart rate variability data to the videogame platform in order to provide biofeedback. The System Usability Scale was completed by patients to determine the usability of e-Estesia.Results and Discussion: e-Estesia performed comparatively well for all the explored groups. Around 84.6% of the patients endorsed that it was easy to use. Female patients with GD presented higher HRV during the use of the serious videogame compared to men. (shrink)

With a focus on appearance and racialised perceptions of skin colour, this paper discusses the differences between being and feeling acceptable, pretty or ugly and the possibility of such displacement (from being to feeling or vice versa), as a way to understand what beauty does in people’s lives. The paper explores the fragility of beauty in relation to the visibility of the body in specific racialised contexts. It investigates the claim that beauty can be considered a feeling that emphasises processes (...) (what beauty does) rather than contents (what beauty is). Drawing from life stories with Mexican women, I examine their concerns about visibility, temporality and appearance as expressions of racist practices and ideas, within a context where the racial project of mestizaje (racial mixture) is in operation. Beauty matters as it makes evident the pervasiveness of racism in the everyday. The lived experience of beauty, in its displacement and fragility, as a feeling and as resource, can also point to some of the strategies to resist, cope and get on. (shrink)

In this article I argue the need for a reflexive use of photographic images in research, mainly in the publication and dissemination phase and specifically when the topic investigated relates to issues of visibility, in this case racism and understandings of beauty. This analysis draws on my work on contemporary practices of racism in Mexico, where personal photographs were used as research tools in life-story interviews, creating a sense of shared intimacy. Inspired by Barthes' refusal in Camera Lucida (2000) to (...) reproduce a photograph of his mother, in this article I focus on the dynamics between seeing and looking and suggest that `looking emotionally' at both participants' accounts and their photographic images, is a way to address the complexities of the gaze and discuss the specificity of different `ways of looking'. The notion of `looking emotionally' refers to an engagement, of researchers and audiences of research, with participants' lived emotional experiences that explicitly confronts the historical and social legacies of the visible. Here, photographs are understood not only as illustrative platforms from where experiences are organized, but also as `traps' that both inform and ensnare (Gell, 1999). As such, the argument aims to problematize the intimate relationship between gaze and photographic image in a context where racism is constrained to the visible, both in its reproduction and also in its pressing ongoing critique. (shrink)

“Artemisa” supone una oportunidad excelente para acercarse al tema de la maternidad desde un punto de vista problemático, alejado de la idealización que, frecuentemente, observamos en tantos textos literarios. En este artículo, trataremos de ver cómo y por qué se fragua en el cuento una visión insoportable del hecho de ser madre, así como una imagen monstruosa del hijo cuya pulsión de vida termina desgastando y debilitando el cuerpo de la mujer a través del amamantamiento forzoso. Por otro lado, reflexionaremos (...) en torno al papel subordinado de Luisa y su interiorización tanto del poder patriarcal como del rol de objeto y no sujeto de deseo. Las principales herramientas metodológicas de nuestro trabajo se desarrollarán desde una perspectiva de género. (shrink)

Este texto introduce un dosier dedicado a reflexionar sobre las relaciones entre el compromiso y la transgresión en la España contemporánea y actual, desde un enfoque de género. Con aportaciones provenientes de la Historia, la Literatura, la Comunicación, la Sociología y la Filosofía, pretende problematizar las jerarquías que suelen establecerse sobre ideales y experiencias desarrollados por mujeres y hombres en ámbitos progresistas o contraculturales. Además, muestra que la trasgresión surge en contextos de activismo intelectual, político, social o feminista al subvertir (...) el orden de género y promover avances en la igualdad, pero no está libre de tensiones y paradojas. (shrink)

The centromere is a specialized chromosomal structure that dictates kinetochore assembly and, thus, is essential for accurate chromosome segregation. Centromere identity is determined epigenetically by the presence of a centromere‐specific histone H3 variant, CENP‐A, that replaces canonical H3 in centromeric chromatin. Here, we discuss recent work by Roulland et al. that identifies structural elements of the nucleosome as essential determinants of centromere function. In particular, CENP‐A nucleosomes have flexible DNA ends due to the short αN helix of CENP‐A. The higher (...) flexibility of the DNA ends of centromeric nucleosomes impairs binding of linker histones H1, while it facilitates binding of other essential centromeric proteins, such as CENP‐C, and is required for mitotic fidelity. This work extends previous observations indicating that the differential structural properties of CENP‐A nucleosomes are on the basis of its contribution to centromere identity and function. Here, we discuss the implications of this work and the questions arising from it. (shrink)

En este texto se hace una introducción y una breve presentación de las distintas contribuciones al dossier. Específicamente, en el texto se precisan los distintos sentidos y perspectivas en los que se han planteado reflexiones filosóficas sobre los distintos aspectos de la educación en América Latina, se muestran algunas líneas temáticas de las reflexiones, se relacionan esas reflexiones con algunos de los planteamientos de la filosofía latinoamericana, se justifica la importancia de continuar y fomentar el trabajo filosófico en este amplio (...) terreno de reflexión filosófica, y se plantean algunos retos para las futuras reflexiones. Finalmente, se presentan y comentan los artículos que forman parte del dossier. (shrink)

BackgroundComorbidity between diabetes mellitus and depression is highly prevalent. The risk of depression in a person with diabetes is approximately twice that of a person without this disease. Depression has a major impact on patient well-being and control of diabetes. However, despite the availability of effective and specific therapeutic interventions for the treatment of depression in people with diabetes, 50% of patients do not receive psychological treatment due to insufficient and difficult accessibility to psychological therapies in health systems. The use (...) of information and communication technologies has therefore been proposed as a useful tool for the delivery of psychological interventions, but it continues to be a field in which scientific evidence is recent and controversial. This systematic review aims to update the available information on the efficacy of psychological interventions delivered through ICTs to improve depressive symptomatology in patients with diabetes.MethodsA systematic review of the literature was performed following the PRISMA guidelines and using MEDLINE, Embase, PubMed, Web of Science, PsycINFO, Scopus, and Cochrane Library databases to search for randomized clinical trials of eHealth treatments for patients with diabetes and comorbid depression from 1995 through 2020. In addition, studies related to follow-up appointments were identified. Inclusion criteria were as follows: randomized clinical trials ; patients with type 1 and type 2 diabetes; adult population over 18 years of age; presence of depressive symptomatology assessed with standardized instruments; treatments for depression based on established psychotherapeutic techniques and principles; delivered through eHealth technologies. We did not limit severity of depressive symptomatology, delivery setting or comparison group. Two coauthors independently reviewed the publications identified for inclusion and extracted data from the included studies. A third reviewer was involved to discuss discrepancies found. The PEDro scale was used to assess the quality of the RCTs. No meta-analysis of the results was performed. The protocol used for this review is available in PROSPERO.ResultsThe initial search identified 427 relevant scientific publications. After removing duplicates and ineligible citations, a total of 201 articles were analyzed in full text. Ten articles met the criteria of this review and were included, obtaining very good scientific quality after evaluation with the PEDro scale. The main results show that the eHealth psychological intervention for depression in patients with diabetes showed beneficial effects both at the end of treatment and in the short and long term for the improvement of depressive symptomatology. The methodology used was very heterogeneous. However, all studies were based on cognitive-behavioral tools and used standardized assessment instruments to evaluate depressive symptomatology or diagnosis of MDD. Glycemic control was assessed by glycosylated hemoglobin, but no benefits were found in improving glycemic control. Only four studies included psychoeducational content on diabetes and depression, but none used tools to improve or enhance adherence to medical prescriptions or diabetes self-care.ConclusionsICT-based psychological interventions for the treatment of depression in people with diabetes appear to be effective in reducing depressive symptomatology but do not appear to provide significant results with regard to glycemic control. Nonetheless, the scientific evidence reported to date is still very limited and the methodology very diverse. In addition, no studies have implemented these systems in routine clinical practice, and no studies are available on the economic analysis of these interventions. Future research should focus on studying and including new tools to ensure improvements in diabetes outcomes and not only on psychological well-being in order to advance knowledge about these treatments. Economic evaluations should also be undertaken to analyze whether these treatment programs implemented using eHealth technologies are cost-effective. (shrink)

Desde una perspectiva transnacional y comparada, que incorpora la experiencia del exilio, este trabajo analiza las tensiones identitarias que afectaron a la juventud militante de la izquierda revolucionaria española y argentina durante los años setenta. A través de las relaciones familiares y de género, estudia las formas públicas y privadas del compromiso y la transgresión. Aborda cómo la politización de lo privado marcó a hombres y mujeres dentro de un proceso global contestatario, heredero del 68, para destacar las contradicciones que (...) afloraron entre la teoría y la práctica, el deseo y la realidad, que llevaron a los jóvenes militantes a asumir un régimen emocional en constante debate entre el ser y el deber ser. (shrink)

The text is part of the investigative concerns from the authors with regard to the dialogue between literature and science teaching. It starts from several theoretical approaches around the general didactics, university or superior didactics, science’s didactics and for last, literature’s didactics. This is largely due to our search which is focused in articulate the university didactics with science and literature’s didactics, meanwhile, we pretend to answer to the questions ¿How are the specific didactics of science and literature going to (...) contribute to the university didactics and how is the last one going to contribute to these specific didactics? ¿Is it the dialogue between science and literature possible? The paper has been made in middle education, in Educative Institution José Miguel de Restrepo y Puerta, from Copacabana and also in university education, in the academic unities of Dietetics and Nutrition School, Agricultural Sciences and Medicine, from the University of Antioquia. Finally, the partial results indicate: i) the necessity of general Didactics as a discipline focused on teaching and learning processes to ask itself for its internal problems and establish relations with specific didactics. (shrink)

The article attempts to verify that inappropriate use of information provided by the media can increase risks for persons who are susceptible to mental illness. The impact of Colombian news in 2014 related to the word suicide was studied to that end. The news was analyzed subsequently through a survey with eight questions applied by two members of the group who had been trained to conduct the study. The idea was to delve deeper and to see the effect of the (...) media and its stigmatization. Nowadays, adolescents are more exposed to situations in which their mood can be affected by improper use of the media, bearing in mind that the worst outcome would be that it leads to suicidal behavior. (shrink)

Tal vez una de las razones por las cuales la tendencia del ser humano a plantearse preguntas que exceden sus posibilidades resulta tan problemática es que nos es imposible negarla o ignorarla. Hacerse preguntas metafísicas pareciera ser un rasgo característicamente humano, e indisociable de su propio cuerpo. Nietzsche muestra que los presupuestos metodológicos del proceder metafísico surgen de tensiones y exigencias fisiológicas, pues la propia relación del cuerpo humano con su entorno conlleva precisamente a la necesidad de ciertas formas de (...) comprensión del mundo. Blumenberg se apoya en esta idea en la medida en que la ausencia de medios biológicos para defenderse de los peligros de la realidad obligan al ser humano a hacer uso de su intelecto y creatividad. Esto conlleva a una forma de relación indirecta y mediada, es decir, metafórica, con el mundo. El objetivo de este artículo es mostrar cómo la perspectiva blumenbergiana complementa e integra las críticas nietzscheanas a la metafísica, de manera que es posible concebir la inclinación natural del hombre a las preguntas metafísicas como su rasgo antropológico característico de su fisiología. (shrink)

Companies that have joined the United Nations Global Compact are required to submit a Communication on Progress, which is an environmental, social, and governance report, to the UNGC every year. If they fail to do so, they are marked and listed as non-communicating on the UNGC website. Using the event study methodology, this study shows that a company that fails to report to the UNGC is penalized in the financial markets with an average cumulative abnormal return of −1.6% over a (...) period of 5 trading days around the event. Although a major critique against the UNGC is that the initiative’s voluntary nature and its lack of external monitoring and sanction mechanisms render it ineffective in terms of the business participants’ implementation of the UNGC principles into their operations, this result suggests that investors may be able to pressure UNGC business participants to increase their compliance with the UNGC requirements and to “walk the talk.”. (shrink)

Dentro de la historiografía centroamericana, el erotismo ha sido un tema que, en contraposición con otros como la reinterpretación del discurso histórico, no cuenta con una cantidad considerable de estudios comparativos que permitan comprender su desarrollo y sus diferentes acercamientos. Con este indicio, el artículo, en aras de enriquecer las discusiones académicas, se centra en dicha temática en cuentos centroamericanos escritos por mujeres, aspecto que en las últimas décadas ha venido tomando un lugar trascendental dentro de los estudios literarios. Específicamente, (...) el análisis parte de textos publicados en el presente siglo y que no han sido estudiados a profundidad por la crítica literaria: “La primera vez” (2002) de la costarricense Linda Berrón, “Diosas decadentes” (2001) de la guatemalteca Jessica Masaya Portocarrero y “Bicho raro” (2012) de la nicaragüense María del Carmen Pérez Cuadra. (shrink)

El objetivo de este trabajo es identificar el significado del papel de la madre, en el desarrollo social, para tres iniciativas de la Renovación de la Pedagogía: la Institución Libre de Enseñanza, las Escuelas del Ave María y la Escuela Moderna de Barcelona. Las fuentes primarias, analizadas para alcanzar dicho fin, son publicaciones de revistas con fines socioeducativos, en su gran mayoría. Y nos advierten de un discurso dispar entre los tres proyectos. Determinando como conclusión principal que las propuestas examinadas (...) tuvieron sus propios planteamientos sobre el significado de madre, pero todas ellas sabían de su importancia como figura educadora. (shrink)

Through cultural transmission, repeated learning by new individuals transforms cultural information, which tends to become increasingly compressible . Existing diffusion chain studies include in their design two processes that could be responsible for this tendency: learning and reproducing . This paper manipulates the presence of learning in a simple iterated drawing design experiment. We find that learning seems to be the causal factor behind the increase in compressibility observed in the transmitted information, while reproducing is a source of random heritable (...) innovations. Only a theory invoking these two aspects of cultural learning will be able to explain human culture's fundamental balance between stability and innovation. (shrink)

Orphan drug policy often gives ‘special treatment’ to rare diseases, by giving additional priority or making exceptions to specific drugs, based on the rarity of the conditions they aim to treat. This essay argues that the goal of orphan drug policy should be to make prevalence irrelevant to funding decisions. It aims to demonstrate that it is severity, not prevalence, which drives our judgments that important claims are being overlooked when treatments for severe rare diseases are not funded. It shows (...) that prioritising severity avoids problems caused by prioritising rarity, and that it is compatible with a range of normative frameworks. The implications of a severity-based view for drug development are then derived. The severity-based view also accounts for what is wrong with how the current system of drug development unfairly neglects common diseases that burden the developing world. Lastly, the implications of a severity-based view for current orphan drug policies are discussed. There are no data in this work. (shrink)

Tanto la preservación del patrimonio arquitectónico como la accesibilidad física, sensorial e intelectual y comunicacional son reconocidos como derechos humanos. Cuando una persona o grupo encuentra condicionada su posibilidad de acceder, usar y disfrutar determinados espacios, sus derechos se encuentran vulnerados. Esto perjudica, principalmente, a personas con discapacidad, personas mayores, personas gestantes, niñas o niños, y tiene un impacto en la vida de todas y todos porque nadie está exento de necesitar condiciones de accesibilidad en algún momento de la vida. (...) Sin embargo, garantizarla en edificios protegidos no es tan sencillo como en una construcción nueva, y la legislación cumple un rol importante que es necesario analizar. En el caso de Argentina, y particularmente de la ciudad de Mar del Plata, se detectan grandes vacíos legales y una notable falta de articulación entre las temáticas, lo que impacta en la realidad material de sus construcciones protegidas. El objetivo de esta investigación es revisar y aportar a ese marco legal desde el enfoque de derechos para convertirlo en una herramienta acorde a los paradigmas actuales, con perspectiva de discapacidad y perspectiva de géneros. Empleando una metodología principalmente cualitativa, recopilando y estudiando de manera crítica una selección de normas que abordan el binomio accesibilidad y patrimonio a escala internacional, nacional y local, se busca contribuir a proteger los valores de los bienes y democratizar su acceso al mismo tiempo. (shrink)

El De dogmatibus ecclesiasticis de Genadio de Marsella se encuentra próximo a la tradición de los símbolos, compilaciones doctrinarias de consulta ágil, por su estructura interna y contenidos. El examen del tratado genadiano contribuye a delimitar su contexto de composición, así como las preferencias dogmáticas de su autor. The De dogmatibus ecclesiasticis of Gennadius of Massilia is close to the tradition of symbols, easy to read doctrinal compilations, because of its structure and contents. The exam of Gennadius’ book contributes to (...) define its composition context and its author’s dogmatic choices. (shrink)

La figura de la mujer de Lot aparece con frecuencia en la predicación de los grandes representantes de la espiritualidad latina de los siglos IV y V, con el propósito de evocar la importancia que tiene la firmeza de los votos para un cristiano comprometido con su fe. Esta figura, además, cuenta con una larga y variada tradición exegética, que será importante tener presente para valorar los aportes de nuestro período específico de interés.

Justifying his proposal for “health savings accounts,” which would allow individuals to set aside tax-free dollars against future healthcare needs, President Bush has said that “Health savings accounts all aim at empowering people to make decisions for themselves.” Who could disagree with such a sentiment? Although bioethicists may be among those who express skepticism that personal health savings accounts will be part of the needed “fix” of our healthcare financing system, self determination has long been part of their mantra. Indeed, (...) the field of bioethics played an important role in advancing this idea in the medical world when physician paternalism was regnant. Has its popularity caused it to become so vapid as to be ripe for misuse? (shrink)

Blockchain is an open digital ledger technology that has the capability of significantly altering the way that people operations operate in organizations. This research takes a first step in proposing several ways in which the blockchain technology can be used to improve current organizational practices, while also considering the ethical implications. Specifically, the paper examines the role that blockchain technology plays in three primary areas of people operations: entry to the organization, intraorganizational processes, and exit. In each section, the paper (...) reviews the ethical implications from the lenses of virtue ethics, utilitarianism, deontology and contractarianism. The paper concludes that in whole the implementation of blockchain technology in people operations processes can create a more ethical work environment. However, careful implementation is necessary and requires extensive examination of ethical implications in advance. (shrink)

The first form of the inside-outside dichotomy appears as a self-encapsulated system with an active border. These systems are based on two complementary but asymmetric processes: constructive and interactive. The former physically constitute the system as a recursive network of component production, defining an inside. The maintenance of the constructive processes implies that the internal organization also constrains certain flows of matter and energy across the border of the system, generating interactive processes. These interactive processes ensure the maintenance of the (...) constructive processes thus specifying a meaningful outside. Upon this basic form of identity formation, the evolutionary and historical domain is open for the emergence of a whole hierarchy and ecology of insides and outsides. These which mutually subsume and collaborate in the maintenance of the essential inside-outside dichotomy that defines the conditions of possibility of the subjects and the worlds they generate. (shrink)

Our goal in this paper is to articulate a precise concept of at least a certain kind of disease-mongering, showing how pharmaceutical marketing can commercially exploit certain diseases when their best definition is given through the success of a treatment in a clinical trial. We distinguish two types of disease-mongering according to the way they exploit the definition of the trial population for marketing purposes. We argue that behind these two forms of disease-mongering there are two well-known problems in the (...) statistical methodology of clinical trials (the reference class problem and the distinction between statistical and clinical significance). Overcoming them is far from simple. (shrink)

This text, commissioned by the OSUN Global Observatory of Academic Freedom, discusses how the concept of academic freedom is codified in Colombian Law and regulations of public and private higher education institutions. It also explores common conceptions of academic freedom among Colombian scholars, as well as commonly observed threats to it.

On September 4, 2001, press reports indicated that the Defense Intelligence Agency of the U.S. Department of Defense planned to reproduce a strain of anthrax virus suspected of being held in Russian laboratories. According to the same reports, the Central Intelligence Agency, under the auspices of Project Clear Vision, is engaged in building replicas of bomblets believed to have been developed by the former Soviet Union. These small bombs were designed to disperse biological agents, including anthrax. Government attorneys were said (...) to be confident that, because these projects were designed to develop defensive measures, they were not in violation of the 1972 Biological and Toxin Weapons Convention. (shrink)

If economics has been the “dismal science” of the past century, health policy promises to be that of the next. Health policy issues evoke far less passion than the emotion-laden immediacies of bedside decision making. Nevertheless, it is patent that “macro” issues in all their obscurity and complexity are unavoidable if the health care delivery system of the future is to be fiscally sound and publicly acceptable. In addition, as Americans are now learning, options for care at the bedside are (...) ineluctably constrained by seemingly distant societal choices. (shrink)